Stability Study of Panchendriyavivardhana Taila, used in Treatment of Cerebral Palsy with respect to Microbiological Study

Miral Dobariya1,*, Meera S Cholera2,Kalpana S Patel3,Virendra Kumar Kori4

1Post graduate scholar, Kaumarbhritya department, Gujarat Ayurved University, IPGT & RA Jamnagar, India
2Head Microbiology Laboratory, Gujarat Ayurved University, IPGT & RA Jamnagar, India
3Professor and Head of the department, Gujarat Ayurved University, Dept. of Kaumarbhritya, IPGT & RA Jamnagar, India
4Assistant Prof., Dept. of Kaumarbhritya, Gujarat Ayurved Universit, IPGT & RA Jamnagar, India

Abstract: Background: Cerebral Palsy is a neurological condition caused by brain damage and it is the most common motor and movement disability of childhood. In present study, Acharya Kashyapokta Panchendriyavivardhana Taila was used. Shelf- life is the time period from when the product is produced until the time it is planned to be consumed or used. Several factors are used to determine a product’s shelf-life, ranging from organoleptic qualities to microbiological safety. Aim: To carried out stability of Panchendriyavivardhana Taila with respect to its stability against microbial contamination. Materials and Methods: Sample of Panchendriyavivardhana Taila was prepared and studied to check microbial contamination at regular time intervals. At the end of study Panchendriyavivardhana Taila container has not presence of microbes for 348 days of preparation sample, even in different climate and temperature. Results: Panchendriyavivardhana Taila was stored in air tight steel container in during different climatric conditions and temperature. Sample was studied at regular intervals for a period of 348 days for to analyze mycological findings and presence of bacteriological findings by Wet mount preparation and Gram stain test respectively. Stability of sample was found at the 32˚C-44˚C range of temperature and 14%-27% of the humidity of environment at respective days. Conclusion: In the microbiological study of Panchendriyavivardhana Taila, there was no growth found of microorganisms from the 5th February 2019 till date 8th January 2020 i.e. 11 months & 3 days even in different climate and temperature. Hence in present study the stability test of Panchendriyavivardhna Taila with respect to microbiological findings was negative at room temperature, warm and cold, dry and humid conditions.


Keywords: Cerebral Palsy, Climate conditions, Microbial profile, Panchendriyavivardhana Taila, Stability.
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References:
  1. Cerebral Palsy, https://en.wikipedia.org/wiki/Cerebral_palsy#cite_note-NINDS2013-1 (Accessed 20th july 2020).
  2. Pandit Hemaraj Sharma ed, Kashyapa Samhita of Vrudhdhajivaka, (Sans)(Hindi), Kalpa Sthana, Shata Kalpa, 32/40, Chaukhambha Vishvabharati: Varanasi, 2015, pp. 279.
  3. 3. Shree Rasiklal Parikh ed, Sharangdhara Samhita, Purva Khanda, Paribhasha Adhyaya, 1/54-56, Sastu Sahitya Vardhaka Karyalaya, Mumbai, 2012, pp.13.
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  5. Shree Rasiklal Parikh ed, Sharangdhara Samhita, Purva Khanda, Paribhasha Adhyaya, 1/54-56, Sastu Sahitya Vardhaka Karyalaya, Mumbai, 2012, pp.13.