Hantaviruses: A Global Life Threatening Disease

Suruchi Agarwal*, Mamta Kumari, Anupam Kr Sachan

Dayanand Dinanath College, Institute of Pharmacy, Ramaipur, Kanpur Nagar-209214, Uttar Pradesh, India.

Abstract: Hantaviruses is an overall rat-borne infection, which has a place with family Bunyaviridae. It essentially causes two clinical symptoms Hantavirus pulmonary syndrome and hemorrhagic fever with renal syndrome. This virus is transmitted from rat to human through inhalation of rodent urine, feces, bite, or dead body. When rats drop their urine, saliva or feces the virus contaminate the air and is inhaled by the person. The person breathes the contaminated air while breeding, aerosols inhalation or excreta so it is also called as air-borne transmission. This virus does not show any appearance on natural hosts but a human related pathogen. It has more than twenty spices of rodent-borne virus, which are negative sense single strand RNA genome. The four spices of natural hosts are deer mouse, white footed mouse; cotton rat and rice rat is main carrier of Hantavirus, which are found in rural areas. It is a zoonotic disease by persistent infection. It was first isolated in America as old and new Hantavirus. It is feverish disease followed by headache, respiratory problems, myalgia, hypotension, cardiovascular disease, hypoxia, back pain, and pulmonary disease. Large, medium, and small sections are found in RNA genome. The replicated enzyme is found as largefragment, medium has envelope glycoprotein, and small has nucleocaspid N.

Keywords:Hantavirus, rodent-virus, inhalation, RNA genome, contaminated, zoonotic.


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